OSAKA: Japanese scientists are conducting clinical trials for a revolutionary drug that could help people regrow missing teeth, offering a natural alternative to dentures and implants.
Katsu Takahashi, head of oral surgery at the Medical Research Institute Kitano Hospital in Osaka, revealed that dormant buds for a third set of teeth exist beneath human gums. This discovery challenges the long-held belief that humans can only grow two sets of teeth.
In October, the team began trials at Kyoto University Hospital, administering the experimental drug to adult volunteers. By targeting the protein USAG-1, which suppresses tooth growth, the drug aims to stimulate the development of new teeth.
Animal studies, including experiments on mice and ferrets, have shown remarkable results. Researchers successfully regrew teeth in animals by blocking USAG-1, and lab images of these regrown teeth provide promising evidence.
“This is a completely new technology,” Takahashi told AFP, highlighting the potential to restore natural teeth and transform dental care.
If successful, this innovation could revolutionize dentistry, improving lives for millions by eliminating the need for artificial solutions to tooth loss.